Like a bunch of folks I have moved over to running 64-bit Windows Server 2008 as the primary OS on my laptop, a Dell D830.
The only problems I've had so far are that when the hypervisor is active sound playback is very poor and graphics performance becomes very poor - resizing a window is very jerky and takes ages. VM performance is great but the host seems to suffer. If you use Virtual PC/Server you'll notice that their performance is awful when the hypervisor is active.
I recently found the solution in this blog post http://blogs.msdn.com/virtual_pc_guy/archive/2008/04/14/creating-a-no-hypervisor-boot-entry.aspx.
You need to create an alternate boot configuration woth the hypervisor loaded. It's a simple fix -
-
Start an administrative command prompt
-
bcdedit /copy {current} /d "Microsoft Windows Server 2008 - no hypervisor"
-
bcdedit /set {identifier for the new boot entry (copy from the output of a plain 'bcdedit' command)} hypervisorlaunchtype off
and next time you boot you can choose to have the hypervisor on or off.